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Med Rx.

Bupivacaine Hydrochloride + Dextrose interactions

Checked as Bupivacaine + Dextrose, unspecified form in this data source.

Full monograph for Bupivacaine Hydrochloride + DextroseCheck it against another medicine

Medicines

215 documented

Medicines documented to interact with Bupivacaine Hydrochloride + Dextrose, worst severity first.
MedicineSeverityMechanismEffectSources
Articaine Hydrochloride + Epinephrine Bitartratevia BupivacaineMajorSynergy · UnknownAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…2 documented mechanisms3 sources — open the full entry
Beclomethasone Dipropionate + Chloramphenicol + Clotrimazole + Lidocainevia BupivacaineMajorSynergy · UnknownAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…2 documented mechanisms3 sources — open the full entry
Benzocaine + Butamben + Tetracaine Hydrochloridevia BupivacaineMajorSynergyAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…2 documented mechanisms10 sources — open the full entry
Betamethasone + Phenylephrine + Lignocainevia BupivacaineMajorSynergyAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…3 sources — open the full entry
Calcium Dobesilate + Lidocaine + Dexamethasonevia BupivacaineMajorSynergy · UnknownAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…2 documented mechanisms3 sources — open the full entry
Chloramphenicol + Lidocaine Hydrochloridevia BupivacaineMajorSynergy · UnknownAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…2 documented mechanisms3 sources — open the full entry
Chloroquine Phosphatevia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Cyclophosphamidevia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Dapsonevia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Diclofenac Sodium + Lidocaine Hydrochloridevia BupivacaineMajorSynergy · UnknownAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…2 documented mechanisms3 sources — open the full entry
Flutamidevia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Hydrocortisone + Lidocainevia BupivacaineMajorSynergy · UnknownAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…2 documented mechanisms3 sources — open the full entry
Hydroxyureavia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Ifosfamidevia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Isosorbide Dinitrate + Hydralazine Hydrochloridevia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Lidocaine + Adrenalinevia BupivacaineMajorSynergy · UnknownAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…2 documented mechanisms3 sources — open the full entry
Lidocaine + Epinephrinevia BupivacaineMajorSynergy · UnknownAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…2 documented mechanisms3 sources — open the full entry
Lidocaine + Prilocainevia BupivacaineMajorSynergyAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…3 documented mechanisms16 sources — open the full entry
Lidocaine HydrochlorideInjectionSprayvia BupivacaineMajorSynergyAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…3 sources — open the full entry
Nitrofurantoinvia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Nitrofurantoin + Nitrofurantoin Microcrystalsvia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Ofloxacin + Clotrimazole + Beclomethasone + Lidocainevia BupivacaineMajorSynergyAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…3 sources — open the full entry
Phenobarbitalvia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Primaquine Phosphatevia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Quinine Sulfatevia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Sulfasalazinevia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…5 sources — open the full entry
Sulphamethoxazole + Trimethoprimvia BupivacaineMajorSynergyCoadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…2 documented mechanisms5 sources — open the full entry
Tolperisone + Lidocainevia BupivacaineMajorSynergyAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…3 sources — open the full entry
Tropicamide + Phenylephrine + Lidocainevia BupivacaineMajorSynergyAdditive toxicities may occur when bupivacaine is coadministered with other local anesthetics. The potential for increased risk of systemic toxicities such as…3 sources — open the full entry
Abametapirvia BupivacaineModerateMetabolismBased on in vitro inhibition data, a single topical application of abametapir lotion may increase plasma concentrations of drugs that are substrates of CYP450…1 sources — open the full entry
Alprazolamvia BupivacaineModerateSynergyThe concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants.7 sources — open the full entry
Amiodarone Hydrochloridevia BupivacaineModerateSynergyAmide-type local anesthetics may have additive cardiac effects (e.g., bradycardia, chest pain, heart block, arrhythmias, ECG abnormalities, cardiac arrest)…2 sources — open the full entry
Amitriptyline Hydrochloride + Chlordiazepoxidevia BupivacaineModerateSynergyThe concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants.7 sources — open the full entry
Amlodipine Besilate + Atenololvia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Aprepitantvia BupivacaineModerateMetabolismCoadministration with aprepitant or its prodrug, fosaprepitant, may increase the plasma concentrations of drugs that are primarily metabolized by CYP450 3A4…2 sources — open the full entry
Atenololvia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Atenolol + Chlorthalidonevia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Betaxolol Hydrochloridevia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Bimatoprost + Timololvia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Bisoprolol Fumaratevia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Bisoprolol Fumarate + Amlodipine Besilatevia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Bisoprolol Fumarate + Hydrochlorothiazidevia BupivacaineModerateSynergy · UnknownBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…2 documented mechanisms3 sources — open the full entry
Brimonidine Tartrate + Timolol Maleatevia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Brinzolamide + Timololvia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Carvedilolvia BupivacaineModerateSynergyBeta-blockers may increase the risk of bupivacaine-induced side effects. The proposed mechanism is increased bupivacaine levels due to hepatic enzyme…3 sources — open the full entry
Cinchocaine + Hydrocortisone + Framycetin + Esculinvia BupivacaineModerateSynergy · UnknownSome topical anesthetics can be systemically absorbed and cause methemoglobinemia, particularly when applied to mucous membranes. Coadministration with other…2 documented mechanisms7 sources — open the full entry
Cinchocaine + Hydrocortisone + Neomycin + Esculinvia BupivacaineModerateSynergy · UnknownSome topical anesthetics can be systemically absorbed and cause methemoglobinemia, particularly when applied to mucous membranes. Coadministration with other…2 documented mechanisms7 sources — open the full entry
Clobazamvia BupivacaineModerateSynergyThe concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants.7 sources — open the full entry
Clonazepamvia BupivacaineModerateSynergyThe concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants.7 sources — open the full entry
Diazepamvia BupivacaineModerateSynergyThe concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants.7 sources — open the full entry

Therapeutic duplication

Drug classes that overlap with Bupivacaine Hydrochloride + Dextrose, so taking both doubles up the same effect. This source publishes no per-row citations for duplication.