Ethinyl Estradiol + Desogestrel (0.03 mg) interactions
Checked as Ethinylestradiol + Desogestrel in this data source.
Full monograph for Ethinyl Estradiol + Desogestrel (0.03 mg)Check it against another medicine
Medicines
332 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Bosentan Monohydratevia Desogestrel, Ethinylestradiol | Major | Metabolism | Coadministration with bosentan may decrease the plasma concentrations and efficacy of contraceptive hormones. The mechanism is bosentan induction of CYP450…2 documented mechanisms | 85 sources — open the full entry |
| Brigatinibvia Desogestrel, Ethinylestradiol | Major | Metabolism | Coadministration with brigatinib may decrease the plasma concentrations of contraceptive hormones. Brigatinib has been shown in vitro to induce CYP450 3A4 at…2 documented mechanisms | 38 sources — open the full entry |
| Carbamazepinevia Desogestrel, Ethinylestradiol | Major | Antagonism · Metabolism | Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may reduce the…2 documented mechanisms | 98 sources — open the full entry |
| Carfilzomibvia Desogestrel, Ethinylestradiol | Major | Synergy | Venous thromboembolic events, including deep vein thrombosis (DVT) and pulmonary embolism (PE), have occurred during treatment with carfilzomib, and concurrent…2 documented mechanisms | 40 sources — open the full entry |
| Dantrolene Sodiumvia Ethinylestradiol | Major | Synergy | The use of estrogens may potentiate the risk of hepatotoxicity associated with dantrolene therapy. The mechanism of interaction is unknown. Fatal and non-fatal… | 39 sources — open the full entry |
| Fosphenytoin Sodiumvia Desogestrel, Ethinylestradiol | Major | Antagonism · Metabolism | Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may reduce the…2 documented mechanisms | 98 sources — open the full entry |
| Glecaprevir + Pibrentasvirvia Ethinylestradiol | Major | Metabolism · Synergy | Coadministration of ethinyl estradiol with glecaprevir-pibrentasvir may increase the risk of alanine aminotransferase (ALT) elevations. ALT elevations are also…2 documented mechanisms | 5 sources — open the full entry |
| Griseofulvin [Ultra Microsize]via Desogestrel, Ethinylestradiol | Major | Metabolism | Limited clinical data suggest that griseofulvin may reduce the efficacy of contraceptive hormones.The proposed mechanism is accelerated clearance of the…2 documented mechanisms | 61 sources — open the full entry |
| Lenalidomidevia Ethinylestradiol | Major | Synergy | Concomitant treatment with agents that can cause thrombosis such as estrogens may potentiate the risk of venous thromboembolic events associated with the use… | 36 sources — open the full entry |
| Mavacamtenvia Desogestrel, Ethinylestradiol | Major | Metabolism | Coadministration with mavacamten may decrease the plasma concentrations and efficacy of contraceptive hormones. The proposed mechanism is mavacamten induction…2 documented mechanisms | 1 sources — open the full entry |
| Mycophenolate Mofetilvia Desogestrel, Ethinylestradiol | Major | Others | Coadministration with mycophenolic acid may decrease the plasma concentrations and, theoretically, the efficacy of contraceptive hormones. The mechanism of…3 documented mechanisms | 39 sources — open the full entry |
| Mycophenolic acidvia Desogestrel, Ethinylestradiol | Major | Others | Coadministration with mycophenolic acid may decrease the plasma concentrations and, theoretically, the efficacy of contraceptive hormones. The mechanism of…2 documented mechanisms | 39 sources — open the full entry |
| Oxcarbazepinevia Desogestrel, Ethinylestradiol | Major | Antagonism · Metabolism | Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may reduce the…3 documented mechanisms | 98 sources — open the full entry |
| Phenobarbitalvia Desogestrel, Ethinylestradiol | Major | Antagonism · Metabolism | Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may reduce the…2 documented mechanisms | 98 sources — open the full entry |
| Phenytoin Sodiumvia Desogestrel, Ethinylestradiol | Major | Antagonism · Metabolism | Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may reduce the…2 documented mechanisms | 98 sources — open the full entry |
| Pomalidomidevia Ethinylestradiol | Major | Synergy | Concomitant treatment with agents that can cause thrombosis such as erythropoiesis-stimulating agents, estrogens, selective estrogen receptor modulators, or C1… | 4 sources — open the full entry |
| Primidonevia Desogestrel, Ethinylestradiol | Major | Antagonism · Metabolism | Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may reduce the…2 documented mechanisms | 98 sources — open the full entry |
| Relugolixvia Ethinylestradiol | Major | Antagonism | Coadministration of hormonal contraceptives may decrease the efficacy of the fixed-dose oral formulation of relugolix, estradiol, and norethindrone when used… | 4 sources — open the full entry |
| Relugolix + Estradiol + Norethindronevia Ethinylestradiol | Major | Antagonism | Coadministration of hormonal contraceptives may decrease the efficacy of the fixed-dose oral formulation of relugolix, estradiol, and norethindrone when used… | 4 sources — open the full entry |
| Rifampicinvia Desogestrel, Ethinylestradiol | Major | Metabolism | Coadministration with rifampin or other rifamycins may reduce the efficacy of contraceptive hormones.The interaction stems from accelerated clearance of…2 documented mechanisms | 145 sources — open the full entry |
| Rifampicin + Isoniazidvia Desogestrel, Ethinylestradiol | Major | Metabolism | Coadministration with rifampin or other rifamycins may reduce the efficacy of contraceptive hormones.The interaction stems from accelerated clearance of…2 documented mechanisms | 145 sources — open the full entry |
| Rifampicin + Isoniazid + Pyrazinamide + Ethambutolvia Desogestrel, Ethinylestradiol | Major | Metabolism | Coadministration with rifampin or other rifamycins may reduce the efficacy of contraceptive hormones.The interaction stems from accelerated clearance of…2 documented mechanisms | 145 sources — open the full entry |
| Thalidomidevia Ethinylestradiol | Major | Synergy | Concomitant treatment with agents that can cause thrombosis such as estrogens may potentiate the risk of venous thromboembolic events associated with the use… | 40 sources — open the full entry |
| Tizanidine Hydrochloridevia Desogestrel, Ethinylestradiol | Major | Metabolism | Coadministration with oral contraceptives may significantly increase the plasma concentrations and pharmacologic effects of tizanidine. The proposed mechanism…3 documented mechanisms | 48 sources — open the full entry |
| Topiramatevia Desogestrel, Ethinylestradiol | Major | Metabolism | Coadministration with topiramate, particularly at dosages above 200 mg/day, may decrease the plasma concentrations and efficacy of contraceptive hormones. The…2 documented mechanisms | 56 sources — open the full entry |
| Tranexamic Acidvia Desogestrel, Ethinylestradiol | Major | Others · Synergy | Because tranexamic acid is an antifibrinolytic agent, concomitant use may further exacerbate the risk of thrombotic events, including venous thromboembolism as…2 documented mechanisms | 44 sources — open the full entry |
| Abametapirvia Desogestrel, Ethinylestradiol | Moderate | Metabolism | Based on in vitro inhibition data, a single topical application of abametapir lotion may increase plasma concentrations of drugs that are substrates of CYP450…2 documented mechanisms | 2 sources — open the full entry |
| Acarbosevia Desogestrel, Ethinylestradiol | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics…2 documented mechanisms | 180 sources — open the full entry |
| Acyclovir + Hydrocortisonevia Ethinylestradiol | Moderate | Synergy | Estrogens may enhance the systemic effects of both endogenous and exogenous corticosteroids. The proposed mechanism is an increase in serum cortisol-binding… | 9 sources — open the full entry |
| Adalimumabvia Desogestrel, Ethinylestradiol | Moderate | Metabolism | Plasma concentrations of drugs that are CYP450 substrates may decrease following the initiation of interleukin (IL) inhibitors, tumor necrosis factor (TNF)…3 documented mechanisms | 34 sources — open the full entry |
| Alogliptin Benzoatevia Desogestrel, Ethinylestradiol | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics…3 documented mechanisms | 180 sources — open the full entry |
| Amikacinvia Ethinylestradiol | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Aminophyllinevia Desogestrel, Ethinylestradiol | Moderate | Metabolism | The coadministration with contraceptive steroids may increase the plasma concentrations of theophylline and other methylxanthines. The proposed mechanism is…2 documented mechanisms | 38 sources — open the full entry |
| Amoxicillin + Clavulanic Acidvia Ethinylestradiol | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Amoxicillin Trihydratevia Ethinylestradiol | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Ampicillin Sodiumvia Ethinylestradiol | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Anastrozolevia Ethinylestradiol | Moderate | Antagonism | Theoretically, estrogen-containing drugs may negate the pharmacologic effects of aromatase inhibitors in the treatment of hormone-dependent breast cancer… | 3 sources — open the full entry |
| Apalutamidevia Desogestrel, Ethinylestradiol | Moderate | Metabolism | Coadministration with inducers of CYP450 3A4 may decrease the plasma concentrations of estrogens and progestins. Estrogens have been shown in in vitro and in…2 documented mechanisms | 97 sources — open the full entry |
| Aprepitantvia Desogestrel, Ethinylestradiol | Moderate | Metabolism | Aprepitant and its prodrug, fosaprepitant, may reduce the efficacy of low-dose hormonal contraceptives during and for up to 28 days after treatment. The…3 documented mechanisms | 38 sources — open the full entry |
| Armodafinilvia Desogestrel, Ethinylestradiol | Moderate | Metabolism | Coadministration with modafinil (the racemate) or armodafinil (the R-enantiomer) may decrease the plasma concentrations of ethinyl estradiol and other…2 documented mechanisms | 53 sources — open the full entry |
| Artemether + Lumefantrinevia Ethinylestradiol | Moderate | Metabolism | RECOMMENDED: Coadministration with artemether may decrease the plasma concentrations of contraceptive hormones. The proposed mechanism is artemether induction…2 documented mechanisms | 39 sources — open the full entry |
| Asciminibvia Desogestrel, Ethinylestradiol | Moderate | Metabolism | Coadministration with asciminib may increase the plasma concentrations of drugs that are primarily metabolized by the CYP450 3A4 isoenzyme. The mechanism is…2 documented mechanisms | 1 sources — open the full entry |
| Azithromycin DihydratebaseOphthalmicvia Ethinylestradiol | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Aztreonamvia Ethinylestradiol | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Bacitracin Zinc + Polymyxin B Sulfatevia Ethinylestradiol | Moderate | Antagonism · Others | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…3 documented mechanisms | 74 sources — open the full entry |
| Beclomethasone Dipropionate + Chloramphenicol + Clotrimazole + Lidocainevia Desogestrel, Ethinylestradiol | Moderate | Antagonism · Metabolism | Azole antifungal agents may increase the plasma concentrations of estrogens and progestins. The mechanism is decreased clearance of the hormones due to…3 documented mechanisms | 52 sources — open the full entry |
| Benzathine Benzylpenicillinvia Ethinylestradiol | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Betamethasonevia Ethinylestradiol | Moderate | Synergy | Estrogens may enhance the systemic effects of both endogenous and exogenous corticosteroids. The proposed mechanism is an increase in serum cortisol-binding… | 9 sources — open the full entry |
| Betamethasone + Calcipotriolvia Ethinylestradiol | Moderate | Synergy | Estrogens may enhance the systemic effects of both endogenous and exogenous corticosteroids. The proposed mechanism is an increase in serum cortisol-binding… | 9 sources — open the full entry |
| Betamethasone + Clotrimazolevia Desogestrel, Ethinylestradiol | Moderate | Metabolism · Synergy | Azole antifungal agents may increase the plasma concentrations of estrogens and progestins. The mechanism is decreased clearance of the hormones due to…3 documented mechanisms | 23 sources — open the full entry |
Therapeutic duplication
Drug classes that overlap with Ethinyl Estradiol + Desogestrel (0.03 mg), so taking both doubles up the same effect. This source publishes no per-row citations for duplication.
estrogens
The recommended maximum number of medicines in the 'estrogens' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'estrogens' category.
Example product in the source data (US market): Oriahnn
estrogens
The recommended maximum number of medicines in the 'estrogens' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'estrogens' category.
Example product in the source data (US market): Estradiol/norethindrone/relugolix