Iron Polymaltose Complex + Folic Acid + Zinc + Vitamin B-Complex interactions
Checked as Iron (polysaccharide) + Folic acid in this data source.
Full monograph for Iron Polymaltose Complex + Folic Acid + Zinc + Vitamin B-ComplexCheck it against another medicine
Medicines
569 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Capecitabinevia Folic acid | Major | Synergy | Coadministration with folate therapy may potentiate the pharmacologic effects of 5-fluorouracil (5-FU). The exact mechanism of interaction is unknown. Although… | 9 sources — open the full entry |
| Fluorouracilvia Folic acid | Major | Synergy | Coadministration with folate therapy may potentiate the pharmacologic effects of 5-fluorouracil (5-FU). The exact mechanism of interaction is unknown. Although… | 9 sources — open the full entry |
| Alendronic acidvia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with…2 documented mechanisms | 6 sources — open the full entry |
| Alendronic Acid + Vitamin D3via Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with…2 documented mechanisms | 6 sources — open the full entry |
| Aluminium Hydroxide + Magnesium Hydroxidevia Iron (polysaccharide) | Moderate | Absorption | The bioavailability of orally administered iron may be reduced by concomitant administration of antacids or other agents with acid-neutralizing effects. The…2 documented mechanisms | 12 sources — open the full entry |
| Aluminium Hydroxide + Magnesium Hydroxide + Simethiconevia Iron (polysaccharide) | Moderate | Absorption | The bioavailability of orally administered iron may be reduced by concomitant administration of antacids or other agents with acid-neutralizing effects. The…2 documented mechanisms | 12 sources — open the full entry |
| Aluminium Oxide + Magnesium Trisilicatevia Iron (polysaccharide) | Moderate | Absorption | The bioavailability of orally administered iron may be reduced by concomitant administration of antacids or other agents with acid-neutralizing effects. The… | 12 sources — open the full entry |
| Baloxavir Marboxilvia Iron (polysaccharide) | Moderate | Absorption | Coadministration with polyvalent cation-containing products may decrease the plasma concentrations and therapeutic efficacy of baloxavir. The proposed… | 1 sources — open the full entry |
| Beclomethasone Dipropionate + Chloramphenicol + Clotrimazole + Lidocainevia Iron (polysaccharide), Folic acid | Moderate | Metabolism · Unknown | Chloramphenicol can cause bone marrow depression and inhibit red blood cell maturation, which may interfere with the therapeutic effects of iron or vitamin B12…4 documented mechanisms | 3 sources — open the full entry |
| Beta carotene + Vitamin C + Vitamin Evia Iron (polysaccharide) | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Calcium acetate + Magnesium carbonatevia Iron (polysaccharide) | Moderate | Absorption | The bioavailability of orally administered iron may be reduced by concomitant administration of antacids or other agents with acid-neutralizing effects. The… | 12 sources — open the full entry |
| Calcium Carbonatevia Iron (polysaccharide) | Moderate | Absorption | The bioavailability of orally administered iron may be reduced by concomitant administration of antacids or other agents with acid-neutralizing effects. The… | 12 sources — open the full entry |
| Calcium Lactate Gluconate + Calcium Carbonate + Vitamin Cvia Iron (polysaccharide) | Moderate | Absorption | The bioavailability of orally administered iron may be reduced by concomitant administration of antacids or other agents with acid-neutralizing effects. The… | 12 sources — open the full entry |
| Calcium Lactate Gluconate + Calcium Carbonate + Vitamin C + Vitamin D3via Iron (polysaccharide) | Moderate | Absorption | The bioavailability of orally administered iron may be reduced by concomitant administration of antacids or other agents with acid-neutralizing effects. The… | 12 sources — open the full entry |
| Calcium Lactate Gluconate + Calcium Carbonate + Vitamin D3via Iron (polysaccharide) | Moderate | Absorption | The bioavailability of orally administered iron may be reduced by concomitant administration of antacids or other agents with acid-neutralizing effects. The… | 12 sources — open the full entry |
| Calcium Lactate Gluconate + Calcium Carbonate + Vitamin D3 + Multimineralsvia Iron (polysaccharide) | Moderate | Absorption | The bioavailability of orally administered iron may be reduced by concomitant administration of antacids or other agents with acid-neutralizing effects. The… | 12 sources — open the full entry |
| Carbamazepinevia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Carbidopa + LevodopaExtended releaseProlonged releasevia Iron (polysaccharide) | Moderate | Absorption | The oral bioavailability and pharmacologic effects of levodopa and carbidopa may be decreased during concurrent administration with iron-containing products… | 4 sources — open the full entry |
| Cefdinirvia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | The oral bioavailability of cefdinir may be significantly decreased by concomitant administration of iron preparations. The proposed mechanism is chelation of…2 documented mechanisms | 2 sources — open the full entry |
| Chloramphenicol (Oral)via Iron (polysaccharide), Folic acid | Moderate | Metabolism · Unknown | Chloramphenicol can cause bone marrow depression and inhibit red blood cell maturation, which may interfere with the therapeutic effects of iron or vitamin B12…2 documented mechanisms | 3 sources — open the full entry |
| Chloramphenicol + Lidocaine Hydrochloridevia Iron (polysaccharide), Folic acid | Moderate | Metabolism · Unknown | Chloramphenicol can cause bone marrow depression and inhibit red blood cell maturation, which may interfere with the therapeutic effects of iron or vitamin B12…3 documented mechanisms | 3 sources — open the full entry |
| CiprofloxacinbaseOphthalmicvia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption…2 documented mechanisms | 32 sources — open the full entry |
| Ciprofloxacin + Dexamethasonevia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption…3 documented mechanisms | 32 sources — open the full entry |
| Ciprofloxacin + Hydrocortisone Acetatevia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption…2 documented mechanisms | 32 sources — open the full entry |
| Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafinevia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption…4 documented mechanisms | 32 sources — open the full entry |
| Deferipronevia Iron (polysaccharide) | Moderate | Antagonism | Deferiprone has the potential to bind polyvalent cations such as aluminum, iron and zinc, which may reduce its effectiveness. However, concurrent use with… | 1 sources — open the full entry |
| Delafloxacinvia Iron (polysaccharide) | Moderate | Absorption | Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption… | 32 sources — open the full entry |
| Dexamethasone + Chloramphenicolvia Iron (polysaccharide), Folic acid | Moderate | Metabolism · Unknown | Chloramphenicol can cause bone marrow depression and inhibit red blood cell maturation, which may interfere with the therapeutic effects of iron or vitamin B12…3 documented mechanisms | 3 sources — open the full entry |
| Dexamethasone + Levofloxacinvia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption…2 documented mechanisms | 32 sources — open the full entry |
| Dexlansoprazolevia Iron (polysaccharide) | Moderate | Absorption | Inhibitors of the proton pump (PPIs or potassium-competitive acid blockers [PCABs]) may impair the gastrointestinal absorption of nonheme iron, a process that… | 12 sources — open the full entry |
| Doxycycline Hydrochloridevia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | The bioavailability of oral tetracyclines and iron salts may be significantly decreased during concurrent administration. Therapeutic failure may result. The…2 documented mechanisms | 11 sources — open the full entry |
| Eltrombopag Olaminevia Iron (polysaccharide) | Moderate | Absorption | Products containing aluminum, calcium, iron, magnesium, zinc and other polyvalent cations such as antacids or mineral supplements can significantly reduce the… | 2 sources — open the full entry |
| EsomeprazolebaseMUPS preparationvia Iron (polysaccharide) | Moderate | Absorption | Inhibitors of the proton pump (PPIs or potassium-competitive acid blockers [PCABs]) may impair the gastrointestinal absorption of nonheme iron, a process that… | 12 sources — open the full entry |
| Esomeprazole + Amoxicillin + Clarithromycinvia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Inhibitors of the proton pump (PPIs or potassium-competitive acid blockers [PCABs]) may impair the gastrointestinal absorption of nonheme iron, a process that…3 documented mechanisms | 12 sources — open the full entry |
| Ethosuximidevia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Ferric Carboxymaltosevia Iron (polysaccharide) | Moderate | Absorption | Parenteral iron therapy may reduce the absorption of concomitantly administered oral iron preparations. | 5 sources — open the full entry |
| Ferric Derisomaltosevia Iron (polysaccharide) | Moderate | Absorption | Parenteral iron therapy may reduce the absorption of concomitantly administered oral iron preparations. | 5 sources — open the full entry |
| Ferric Pyrophosphate Citratevia Iron (polysaccharide) | Moderate | Absorption | Parenteral iron therapy may reduce the absorption of concomitantly administered oral iron preparations. | 5 sources — open the full entry |
| Fosphenytoin Sodiumvia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Gatifloxacinvia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption…2 documented mechanisms | 32 sources — open the full entry |
| Gatifloxacin + Dexamethasonevia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption…3 documented mechanisms | 32 sources — open the full entry |
| Gemifloxacinvia Iron (polysaccharide) | Moderate | Absorption | Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics. Absorption… | 32 sources — open the full entry |
| Ibandronic Acidvia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with…2 documented mechanisms | 6 sources — open the full entry |
| Ibandronic Acid + Algae Calcium + Vitamin D3via Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with…2 documented mechanisms | 6 sources — open the full entry |
| Ibandronic Acid + Coral Calcium + Vitamin D3via Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with…2 documented mechanisms | 6 sources — open the full entry |
| Iron Sucrosevia Iron (polysaccharide) | Moderate | Absorption | Parenteral iron therapy may reduce the absorption of concomitantly administered oral iron preparations. | 5 sources — open the full entry |
| Lamotriginevia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Lansoprazolevia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Inhibitors of the proton pump (PPIs or potassium-competitive acid blockers [PCABs]) may impair the gastrointestinal absorption of nonheme iron, a process that…2 documented mechanisms | 12 sources — open the full entry |
| Lansoprazole + Amoxicillin + Clarithromycinvia Iron (polysaccharide), Folic acid | Moderate | Absorption · Unknown | Inhibitors of the proton pump (PPIs or potassium-competitive acid blockers [PCABs]) may impair the gastrointestinal absorption of nonheme iron, a process that…4 documented mechanisms | 12 sources — open the full entry |
| Lanthanum Carbonatevia Iron (polysaccharide) | Moderate | Absorption | Theoretically, lanthanum carbonate may chelate with certain drugs in the gastrointestinal tract, resulting in reduced oral bioavailability of those drugs… | 6 sources — open the full entry |
Food & lifestyle
alcohol
ModerateSynergy
Ethanol may increase folic acid elimination and folic acid absorption is decreased in chronic alcoholics. Excessive alcohol consumption may lead to folate deficiency.
What to do: Monitoring of patient response to folic acid supplementation if they also consume alcohol regularly may be recommended.
5 sources
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- Agencia Espa?ola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaci��n online de medicamentos de la AEMPS - CIMA. https://cima.aemps.es/cima/publico/home.html" (2008):
- Cerner Multum, Inc "ANVISA Bul��rio Eletr?nico." O 0 (2015):
- "Product Information. Folic Acid (folic acid)." Method Pharmaceuticals, LLC (2017):
Conditions
Conditions in which Iron Polymaltose Complex + Folic Acid + Zinc + Vitamin B-Complex needs care, as documented in this source.
Anemia
MajorThe use of folic acid is contraindicated in patients with undiagnosed anemia. Folic acid in dosages above 1 mg/day can obscure the diagnosis of pernicious anemia by alleviating the hematologic abnormalities while allowing the progression of neurologic complications. In addition, folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient.
3 sources
- Butterworth CE Jr, Tamura T "Folic acid safety and toxicity: a brief review." Am J Clin Nutr 50 (1989): 353-8
- Katz M "Potential danger of self-medication with folic acid." N Engl J Med 289 (1973): 1095
- "Product Information. Renal Multivitamin Formula Rx (folic acid)." Vitaline Corporation, Ashland, OR.