Skip to content
Med Rx.

Isoflurane interactions

Full monograph for IsofluraneCheck it against another medicine

Medicines

179 documented

Medicines documented to interact with Isoflurane, worst severity first.
MedicineSeverityMechanismEffectSources
AdrenalineMajorOthersRarely, the combination of epinephrine and some anesthetics has resulted in ventricular irritability, serious cardiac arrhythmias, or death. The halogenated…20 sources — open the full entry
Articaine Hydrochloride + Epinephrine BitartrateMajorOthersRarely, the combination of epinephrine and some anesthetics has resulted in ventricular irritability, serious cardiac arrhythmias, or death. The halogenated…20 sources — open the full entry
Lidocaine + AdrenalineMajorOthers · UnknownRarely, the combination of epinephrine and some anesthetics has resulted in ventricular irritability, serious cardiac arrhythmias, or death. The halogenated…2 documented mechanisms20 sources — open the full entry
Lidocaine + EpinephrineMajorOthers · UnknownRarely, the combination of epinephrine and some anesthetics has resulted in ventricular irritability, serious cardiac arrhythmias, or death. The halogenated…2 documented mechanisms20 sources — open the full entry
Norepinephrine TartrateMajorOthersThe combination of norepinephrine and some anesthetics has resulted in ventricular irritability, serious cardiac arrhythmias, or death. The halogenated…21 sources — open the full entry
Amiodarone HydrochlorideModerateSynergyAmiodarone may increase the pharmacologic effects of isoflurane because of the adrenergic blocking effects of amiodarone. Data have been conflicting; however…6 sources — open the full entry
Amitriptyline HydrochlorideModerateSynergyThe concomitant use of general anesthetics with tricyclic antidepressants may increase the risk of hypotension and cardiac arrhythmias. The presence of…1 sources — open the full entry
Amitriptyline Hydrochloride + ChlordiazepoxideModerateOthers · SynergyThe concomitant use of general anesthetics with tricyclic antidepressants may increase the risk of hypotension and cardiac arrhythmias. The presence of…2 documented mechanisms6 sources — open the full entry
Amlodipine BesilateModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Amlodipine Besilate + AtenololModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Amlodipine Besilate + AtorvastatinModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Amlodipine Besilate + Benazepril HydrochlorideModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Amlodipine Besilate + Olmesartan MedoxomilModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Amlodipine Besilate + TelmisartanModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Amlodipine Besilate + ValsartanModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Atracurium BesilateModerateSynergyInhalation anesthetics may potentiate the effects of nondepolarizing muscle relaxants. Long-acting muscle relaxants such as pancuronium and d-tubocurarine are…9 sources — open the full entry
BaclofenModerateSynergyThe concomitant or sequential use of intrathecal baclofen and general anesthetics may increase the risk of seizures and cardiovascular disturbances, and…6 sources — open the full entry
Bisoprolol Fumarate + Amlodipine BesilateModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
CeritinibModerateMetabolismCoadministration with ceritinib may increase the plasma concentration and the risk of adverse effects of drugs that are substrates of CYP450 2A6 and/or 2E1…8 sources — open the full entry
Cisatracurium BesylateModerateSynergyInhalation anesthetics may potentiate the effects of nondepolarizing muscle relaxants. Long-acting muscle relaxants such as pancuronium and d-tubocurarine are…9 sources — open the full entry
Clomipramine HydrochlorideModerateSynergyThe concomitant use of general anesthetics with tricyclic antidepressants may increase the risk of hypotension and cardiac arrhythmias. The presence of…1 sources — open the full entry
Diltiazem HydrochlorideModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Doxepin (Oral)ModerateSynergyThe concomitant use of general anesthetics with tricyclic antidepressants may increase the risk of hypotension and cardiac arrhythmias. The presence of…1 sources — open the full entry
Fentanyl CitrateModerateOthersSeveral cases of hypotension and general cutaneous flushing have been reported in patients receiving fentanyl and isoflurane. The mechanism of this interaction…7 sources — open the full entry
Fluphenazine + NortriptylineModerateSynergyThe concomitant use of general anesthetics with tricyclic antidepressants may increase the risk of hypotension and cardiac arrhythmias. The presence of…1 sources — open the full entry
Imipramine HydrochlorideModerateSynergyThe concomitant use of general anesthetics with tricyclic antidepressants may increase the risk of hypotension and cardiac arrhythmias. The presence of…1 sources — open the full entry
Indapamide + AmlodipineModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Levamlodipine MaleateModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Methylphenidate HydrochlorideModerateSynergyThe administration of volatile general anesthetics during methylphenidate therapy may increase the risk of hypertension and/or arrhythmias during surgery. The…6 sources — open the full entry
Morphine SulfateModerateSynergyOpioids may be expected to decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly, less…3 sources — open the full entry
Nalbuphine HydrochlorideModerateSynergyOpioids may be expected to decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly, less…3 sources — open the full entry
NifedipineModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
NimodipineModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
NortriptylineModerateSynergyThe concomitant use of general anesthetics with tricyclic antidepressants may increase the risk of hypotension and cardiac arrhythmias. The presence of…1 sources — open the full entry
Oxymorphone HydrochlorideModerateSynergyOpioids may be expected to decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly, less…3 sources — open the full entry
Pancuronium BromideModerateSynergyInhalation anesthetics may potentiate the effects of nondepolarizing muscle relaxants. Long-acting muscle relaxants such as pancuronium and d-tubocurarine are…9 sources — open the full entry
Paracetamol + Tramadol HydrochlorideModerateSynergy · UnknownOpioids may decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly, less inhalation…2 documented mechanisms2 sources — open the full entry
PentazocineModerateSynergyOpioids may be expected to decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly, less…3 sources — open the full entry
Perindopril Arginine + AmlodipineModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
Pethidine HydrochlorideModerateSynergyOpioids may be expected to decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly, less…3 sources — open the full entry
PropofolModerateSynergyAdditive central nervous system and cardiorespiratory depressant effects may occur when fospropofol or propofol is administered with other depressants such as…6 sources — open the full entry
Remifentanil HydrochlorideModerateSynergyOpioids may be expected to decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly, less…3 sources — open the full entry
Rifampicin + IsoniazidModerateSynergyNephrotoxic concentrations of inorganic fluoride may occur in patients receiving enflurane anesthesia while on isoniazid therapy. A similar effect has been…9 sources — open the full entry
Rifampicin + Isoniazid + Pyrazinamide + EthambutolModerateSynergyNephrotoxic concentrations of inorganic fluoride may occur in patients receiving enflurane anesthesia while on isoniazid therapy. A similar effect has been…9 sources — open the full entry
Rocuronium BromideModerateSynergyInhalation anesthetics may potentiate the effects of nondepolarizing muscle relaxants. Long-acting muscle relaxants such as pancuronium and d-tubocurarine are…9 sources — open the full entry
Suxamethonium ChlorideModerateSynergyInhalation anesthetics may potentiate the effects of nondepolarizing muscle relaxants. Long-acting muscle relaxants such as pancuronium and d-tubocurarine are…9 sources — open the full entry
Tramadol HydrochlorideModerateSynergyOpioids may decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly, less inhalation…2 sources — open the full entry
Vecuronium BromideModerateSynergyInhalation anesthetics may potentiate the effects of nondepolarizing muscle relaxants. Long-acting muscle relaxants such as pancuronium and d-tubocurarine are…9 sources — open the full entry
Verapamil HydrochlorideModerateSynergyCalcium channel blockers may potentiate the cardiac depressant and hypotensive effects of volatile (halogenated) anesthetics, and vice versa, due to their…35 sources — open the full entry
AlprazolamMinorOthersBenzodiazepines may be expected to decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly…5 sources — open the full entry

This source documents no food, condition or duplication entries for Isoflurane.