Skip to content
Med Rx.

Amantadine Hydrochloride interactions

Checked as Amantadine in this data source.

Full monograph for Amantadine HydrochlorideCheck it against another medicine

Medicines

298 documented

Medicines documented to interact with Amantadine Hydrochloride, worst severity first.
MedicineSeverityMechanismEffectSources
Bupropion HydrochlorideMajorSynergyThe use of bupropion is associated with a dose-related risk of seizures. The risk may also be increased during coadministration of bupropion with other…13 sources — open the full entry
Dextromethorphan + BupropionMajorSynergyThe use of bupropion is associated with a dose-related risk of seizures. The risk may also be increased during coadministration of bupropion with other…13 sources — open the full entry
IohexolMajorSynergyIntrathecal administration of iodinated contrast media may induce seizures. Although clinical data are generally lacking, there may be a theoretical risk of…5 sources — open the full entry
IopamidolMajorSynergyIntrathecal administration of iodinated contrast media may induce seizures. Although clinical data are generally lacking, there may be a theoretical risk of…5 sources — open the full entry
Paracetamol + Tramadol HydrochlorideMajorSynergy · UnknownThe risk of seizures may be increased during coadministration of tramadol with any substance that can reduce the seizure threshold, such as selective serotonin…2 documented mechanisms8 sources — open the full entry
Tramadol HydrochlorideMajorSynergyThe risk of seizures may be increased during coadministration of tramadol with any substance that can reduce the seizure threshold, such as selective serotonin…8 sources — open the full entry
Amitriptyline HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Amitriptyline Hydrochloride + ChlordiazepoxideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
AripiprazoleModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Asenapine MaleateModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Atropine Sulfate (Injection)ModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Beclometasone + Formoterol + GlycopyrroniumModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
BrexpiprazoleModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Budesonide + Glycopyrronium Bromide + Formoterol FumarateModerateSynergy · UnknownThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…2 documented mechanisms6 sources — open the full entry
CariprazineModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Chlorpheniramine MaleateModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Chlorpromazine HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Cinnarizine + DimenhydrinateModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Clomipramine HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
ClozapineModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Cyclizine HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Cyclobenzaprine HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
DarifenacinModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Dextromethorphan + Phenylephrine + TriprolidineModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Dextromethorphan + Pseudoephedrine + TriprolidineModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Dicycloverine HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Diphenhydramine + Dextromethorphan + LevomentholModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Diphenhydramine + LevomentholModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Diphenhydramine HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Diphenhydramine Hydrochloride + Zinc AcetateModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Doxepin (Oral)ModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Doxepin (Topical)ModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Flavoxate HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
FlibanserinModerateSynergyThe central nervous system (CNS) effects of flibanserin such as somnolence and fatigue may be potentiated by concomitant use of other agents with CNS…6 sources — open the full entry
Fluphenazine + NortriptylineModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…2 documented mechanisms6 sources — open the full entry
Fluphenazine DecanoateModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Formoterol Fumarate + Glycopyrrolate + BudesonideModerateSynergy · UnknownThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…2 documented mechanisms6 sources — open the full entry
Glycopyrronium BromideInhalation capsuleInjectionOral solutionRespirator SolutionModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Glycopyrronium Bromide + Formoterol FumarateModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Guaifenesin + Levomenthol + DiphenhydramineModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
HaloperidolModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Homatropine HydrobromideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…2 sources — open the full entry
Hydroxyzine HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Hyoscine ButylbromideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Hyoscine HydrobromideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
IfosfamideModerateSynergyCentrally-acting agents such as antiemetics, sedatives, narcotics, or antihistamines may add to the neurotoxic effects of ifosfamide. Administration of…6 sources — open the full entry
IloperidoneModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Imipramine HydrochlorideModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Indacaterol + GlycopyrroniumModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry
Indacaterol + Glycopyrronium + Mometasone FuroateModerateSynergyThe anticholinergic-like adverse effects of amantadine may be potentiated by agents with anticholinergic properties such as antihistamines, antispasmodics…6 sources — open the full entry

Conditions

Conditions in which Amantadine Hydrochloride needs care, as documented in this source.

Therapeutic duplication

Drug classes that overlap with Amantadine Hydrochloride, so taking both doubles up the same effect. This source publishes no per-row citations for duplication.