Memantine Hydrochloride interactions
Checked as Memantine in this data source.
Full monograph for Memantine HydrochlorideCheck it against another medicine
Medicines
371 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Amitriptyline Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Amitriptyline Hydrochloride + Chlordiazepoxide | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Aripiprazole | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Asenapine Maleate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Atropine Sulfate (Injection) | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Beclometasone + Formoterol + Glycopyrronium | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Brexpiprazole | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Budesonide + Glycopyrronium Bromide + Formoterol Fumarate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Cariprazine | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Chlorpheniramine Maleate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Chlorpromazine Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Cinnarizine + Dimenhydrinate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Clomipramine Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Clozapine | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Cyclizine Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Cyclobenzaprine Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Darifenacin | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Dextromethorphan + Phenylephrine + Triprolidine | Moderate | Others · Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic…2 documented mechanisms | 24 sources — open the full entry |
| Dextromethorphan + Pseudoephedrine + Triprolidine | Moderate | Others · Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic…2 documented mechanisms | 24 sources — open the full entry |
| Dicycloverine Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Diphenhydramine + Dextromethorphan + Levomenthol | Moderate | Others · Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic…2 documented mechanisms | 24 sources — open the full entry |
| Diphenhydramine + Levomenthol | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Diphenhydramine Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Diphenhydramine Hydrochloride + Zinc Acetate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Doxepin (Oral) | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Doxepin (Topical) | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Fesoterodine Fumarate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Flavoxate Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Fluphenazine + Nortriptyline | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic…2 documented mechanisms | 19 sources — open the full entry |
| Fluphenazine Decanoate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Formoterol Fumarate + Glycopyrrolate + Budesonide | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Glycopyrronium BromideInhalation capsuleInjectionOral solutionRespirator Solution | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Glycopyrronium Bromide + Formoterol Fumarate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Guaifenesin + Levomenthol + Diphenhydramine | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Haloperidol | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Hydroxyzine Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Hyoscine Butylbromide | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Hyoscine Hydrobromide | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Iloperidone | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Imipramine Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Indacaterol + Glycopyrronium | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Indacaterol + Glycopyrronium + Mometasone Furoate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Lurasidone Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Maprotiline Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Meclizine + Pyridoxine | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Meclizine Hydrochloride | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Nortriptyline | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Olanzapine | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Paliperidone | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
| Paliperidone Palmitate | Moderate | Synergy | Agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic… | 19 sources — open the full entry |
Conditions
Conditions in which Memantine Hydrochloride needs care, as documented in this source.
Hepatic Insufficiency
ModerateMemantine should be used with caution in patients with severe hepatic impairment and a dosage reduction is recommended. No dosage adjustment is needed in patients with mild or moderate hepatic impairment.
1 source
- "Product Information. Namenda (memantine)." Forest Pharmaceuticals (2003):
Kidney Diseases
ModerateMemantine renal clearance involves active tubular secretion moderated by pH dependent tubular reabsorption and conditions that raise urine pH may increase the plasma levels of memantine. Therapy with memantine should be used cautiously in patients with conditions that raise urine pH, such as renal tubular acidosis or severe infections of the urinary tract. Additionally, memantine should be used with caution in patients with severe renal impairment and a dosage reduction is recommended. No dosage adjustment is needed in patients with mild or moderate renal impairment.
1 source
- "Product Information. Namenda (memantine)." Forest Pharmaceuticals (2003):
Therapeutic duplication
Drug classes that overlap with Memantine Hydrochloride, so taking both doubles up the same effect. This source publishes no per-row citations for duplication.
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Bupropion/dextromethorphan
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Tylenol cold multi-symptom severe
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Robitussin cold cough and flu
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Vicks 44d
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Sutan-dm
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Resperal-dm
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Nuedexta
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Mucinex nightshift sinus clear & cool
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Bromhist-pdx
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Supress a pediatric
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Phlemex
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Dextromethorphan/diphenhydramine/phenylephrine
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Dextromethorphan/pyrilamine
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Robitussin cough & cold d
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Acetaminophen/chlorpheniramine/dextromethorphan/pseudoephedrine
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Nohist dm
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Brompheniramine/dextromethorphan/phenylephrine
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Triaminic softchews cough & sore throat
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Diabetic tussin night time formula
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Phlemex forte
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Vicks nyquil cold & flu nighttime relief
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): M-end dmx
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Robitussin peak cold daytime cold + flu
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Aspirin/chlorpheniramine/dextromethorphan/phenylpropanolamine
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Mucinex nightshift cold & flu
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Chlorpheniramine/dextromethorphan/pseudoephedrine
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Robitussin children's cough & cold long-acting
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Pediacare children's multi-symptom cold
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Vicks nyquil severe cold & flu
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Vicks nyquil cough
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Vicks nyquil d cold and flu nighttime relief
nmda antagonists
The recommended maximum number of medicines in the 'NMDA antagonists' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'NMDA antagonists' category.
Example product in the source data (US market): Promethazine dm