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Salicylic Acid interactions

Full monograph for Salicylic AcidCheck it against another medicine

Medicines

267 documented

Medicines documented to interact with Salicylic Acid, worst severity first.
MedicineSeverityMechanismEffectSources
AcetazolamideMajorOthersThe combination of large doses of salicylates and oral carbonic anhydrase inhibitors (CAI) may rarely result in severe metabolic acidosis and/or salicylate…16 sources — open the full entry
DeferasiroxMajorSynergyCoadministration with nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding associated with the use of deferasirox.2 sources — open the full entry
Dorzolamide + TimololMajorAntagonism · OthersThe combination of large doses of salicylates and oral carbonic anhydrase inhibitors (CAI) may rarely result in severe metabolic acidosis and/or salicylate…2 documented mechanisms22 sources — open the full entry
Ketorolac TromethamineMajorSynergyThe use of ketorolac in combination with other nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of serious adverse effects such as renal…1 sources — open the full entry
LeflunomideMajorSynergyThe recent, concomitant, or subsequent use (without the recommended leflunomide washout period or procedure) of other agents known to induce hepatotoxicity…3 sources — open the full entry
MethotrexateMajorDistribution · ExcretionSalicylates may interfere with the renal elimination of methotrexate and may displace it from binding sites.16 sources — open the full entry
Monobasic Sodium Phosphate + Dibasic Sodium PhosphateMajorOthersThe following interaction applies only to products containing sodium biphosphate that are used for bowel cleansing. It does not apply to products containing…3 sources — open the full entry
RamucirumabMajorSynergyTheoretical concerns exist that nonsteroid anti-inflammatory drugs (NSAIDs) and salicylates may potentiate the risk of bleeding and gastrointestinal…1 sources — open the full entry
Activated CharcoalModerateAbsorptionCharcoal may reduce the absorption of many drugs and can absorb enterohepatically circulated drugs.25 sources — open the full entry
Acyclovir + HydrocortisoneModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Alendronic acidModerateSynergyTheoretical concerns exist regarding the potential for increased risk and severity of gastrointestinal toxicity during coadministration of oral bisphosphonates…11 sources — open the full entry
Alendronic Acid + Vitamin D3ModerateSynergyTheoretical concerns exist regarding the potential for increased risk and severity of gastrointestinal toxicity during coadministration of oral bisphosphonates…11 sources — open the full entry
Allium cepa + Heparin + AllantoinModerateSynergyTheoretically, salicylates may potentiate the effects of anticoagulants and increase the risk of bleeding.8 sources — open the full entry
AlteplaseModerateSynergyDrugs that inhibit platelet function may increase the risk of bleeding when administered prior to, during, or after thrombolytic therapy.8 sources — open the full entry
Aluminium Hydroxide + Magnesium HydroxideModerateExcretionChronic administration of antacids may reduce serum salicylate concentrations in patients receiving large doses of aspirin or other salicylates. The mechanism…2 documented mechanisms8 sources — open the full entry
Aluminium Hydroxide + Magnesium Hydroxide + SimethiconeModerateExcretionChronic administration of antacids may reduce serum salicylate concentrations in patients receiving large doses of aspirin or other salicylates. The mechanism…2 documented mechanisms8 sources — open the full entry
Aluminium Oxide + Magnesium TrisilicateModerateExcretionChronic administration of antacids may reduce serum salicylate concentrations in patients receiving large doses of aspirin or other salicylates. The mechanism…8 sources — open the full entry
AmikacinModerateSynergyThe nephrotoxic effect of aminoglycosides may be potentiated by nonsteroidal anti-inflammatory drugs (NSAIDs), particularly if the latter had been given in…6 sources — open the full entry
Amlodipine BesilateModerateAntagonismLimited data indicate that some cyclooxygenase inhibitors may attenuate the antihypertensive effects of some calcium channel blockers. The mechanism appears to…9 sources — open the full entry
Amlodipine Besilate + AtenololModerateAntagonismLimited data indicate that some cyclooxygenase inhibitors may attenuate the antihypertensive effects of some calcium channel blockers. The mechanism appears to…2 documented mechanisms15 sources — open the full entry
Amlodipine Besilate + AtorvastatinModerateAntagonismLimited data indicate that some cyclooxygenase inhibitors may attenuate the antihypertensive effects of some calcium channel blockers. The mechanism appears to…9 sources — open the full entry
Amlodipine Besilate + Benazepril HydrochlorideModerateAntagonismLimited data indicate that some cyclooxygenase inhibitors may attenuate the antihypertensive effects of some calcium channel blockers. The mechanism appears to…2 documented mechanisms22 sources — open the full entry
Amlodipine Besilate + Olmesartan MedoxomilModerateAntagonismLimited data indicate that some cyclooxygenase inhibitors may attenuate the antihypertensive effects of some calcium channel blockers. The mechanism appears to…2 documented mechanisms13 sources — open the full entry
Amlodipine Besilate + TelmisartanModerateAntagonismLimited data indicate that some cyclooxygenase inhibitors may attenuate the antihypertensive effects of some calcium channel blockers. The mechanism appears to…2 documented mechanisms13 sources — open the full entry
Amlodipine Besilate + ValsartanModerateAntagonismLimited data indicate that some cyclooxygenase inhibitors may attenuate the antihypertensive effects of some calcium channel blockers. The mechanism appears to…2 documented mechanisms13 sources — open the full entry
ApixabanModerateSynergyTheoretically, salicylates may potentiate the effects of anticoagulants and increase the risk of bleeding.8 sources — open the full entry
AspirinModerateSynergyConcomitant use of more than one salicylate at a time may increase the potential for gastrointestinal adverse effects (e.g., inflammation, pain, bleeding…2 sources — open the full entry
Aspirin + DipyridamoleModerateSynergyConcomitant use of more than one salicylate at a time may increase the potential for gastrointestinal adverse effects (e.g., inflammation, pain, bleeding…2 sources — open the full entry
Azilsartan MedoxomilModerateAntagonismNonsteroidal anti-inflammatory drugs (NSAIDs) may attenuate the antihypertensive effects of angiotensin II receptor antagonists. The proposed mechanism is…4 sources — open the full entry
Azilsartan Medoxomil + ChlorthalidoneModerateAntagonismNonsteroidal anti-inflammatory drugs (NSAIDs) may attenuate the antihypertensive effects of angiotensin II receptor antagonists. The proposed mechanism is…4 sources — open the full entry
BaricitinibModerateSynergyCoadministration of Janus kinase (JAK) inhibitors with corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), and/or opioids may increase the risk of…15 sources — open the full entry
BetamethasoneModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Betamethasone + CalcipotriolModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Betamethasone + ClotrimazoleModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Betamethasone + Clotrimazole + GentamicinModerateExcretion · Metabolism · SynergyCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…2 documented mechanisms11 sources — open the full entry
Betamethasone + Neomycin Sulphate (Ophthalmic)ModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Betamethasone + Phenylephrine + LignocaineModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Betamethasone DipropionateModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Betamethasone Dipropionate + Salicylic AcidModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Betamethasone Sodium PhosphateModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Betamethasone ValerateModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
BetrixabanModerateSynergyTheoretically, salicylates may potentiate the effects of anticoagulants and increase the risk of bleeding.8 sources — open the full entry
Biphasic Insulin AspartModerateSynergyThe hypoglycemic effect of insulin may be potentiated by certain drugs, including ACE inhibitors, angiotensin receptor blockers (ARBs), 4-aminoquinolines…76 sources — open the full entry
Bismuth SubsalicylateModerateSynergyConcomitant use of more than one salicylate at a time may increase the potential for gastrointestinal adverse effects (e.g., inflammation, pain, bleeding…2 sources — open the full entry
Bisoprolol Fumarate + Amlodipine BesilateModerateAntagonismLimited data indicate that some cyclooxygenase inhibitors may attenuate the antihypertensive effects of some calcium channel blockers. The mechanism appears to…2 documented mechanisms15 sources — open the full entry
BivalirudinModerateSynergyTheoretically, salicylates may potentiate the effects of anticoagulants and increase the risk of bleeding.8 sources — open the full entry
BudesonideInhalerNebuliser SuspensionTabletModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Budesonide + Formoterol FumarateModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Budesonide + Glycopyrronium Bromide + Formoterol FumarateModerateExcretion · MetabolismCoadministration with corticosteroids may decrease the serum concentrations and therapeutic effects of salicylates. Likewise, serum salicylate levels may…5 sources — open the full entry
Calcium acetate + Magnesium carbonateModerateExcretionChronic administration of antacids may reduce serum salicylate concentrations in patients receiving large doses of aspirin or other salicylates. The mechanism…8 sources — open the full entry

Therapeutic duplication

Drug classes that overlap with Salicylic Acid, so taking both doubles up the same effect. This source publishes no per-row citations for duplication.