Vitamin A interactions
Full monograph for Vitamin ACheck it against another medicine
Medicines
117 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Acitretin | Major | Synergy | Concomitant use of a retinoid with vitamin A or other retinoids may result in hypervitaminosis A and additive toxicities. Patients may be at increased risk for… | 5 sources — open the full entry |
| Clindamycin + Tretinoin | Major | Synergy | Concomitant use of a retinoid with vitamin A or other retinoids may result in hypervitaminosis A and additive toxicities. Patients may be at increased risk for… | 5 sources — open the full entry |
| Doxycycline Hydrochloride | Major | Synergy | Concomitant use of vitamin A or related compounds (i.e., retinoids) with tetracyclines may increase the risk of pseudotumor cerebri, also known as benign… | 23 sources — open the full entry |
| Fluocinolone Acetonide + Hydroquinone + Tretinoin | Major | Synergy | Concomitant use of a retinoid with vitamin A or other retinoids may result in hypervitaminosis A and additive toxicities. Patients may be at increased risk for… | 5 sources — open the full entry |
| IsotretinoinOralTopical | Major | Synergy | Concomitant use of a retinoid with vitamin A or other retinoids may result in hypervitaminosis A and additive toxicities. Patients may be at increased risk for… | 5 sources — open the full entry |
| Minocycline Hydrochloride | Major | Synergy | Concomitant use of vitamin A or related compounds (i.e., retinoids) with tetracyclines may increase the risk of pseudotumor cerebri, also known as benign… | 23 sources — open the full entry |
| Oxytetracycline | Major | Synergy | Concomitant use of vitamin A or related compounds (i.e., retinoids) with tetracyclines may increase the risk of pseudotumor cerebri, also known as benign… | 23 sources — open the full entry |
| Oxytetracycline + Polymixin B Sulphate | Major | Synergy | Concomitant use of vitamin A or related compounds (i.e., retinoids) with tetracyclines may increase the risk of pseudotumor cerebri, also known as benign… | 23 sources — open the full entry |
| Tetracycline Hydrochloride | Major | Synergy | Concomitant use of vitamin A or related compounds (i.e., retinoids) with tetracyclines may increase the risk of pseudotumor cerebri, also known as benign… | 23 sources — open the full entry |
| Tretinoin (Oral) | Major | Synergy | Concomitant use of a retinoid with vitamin A or other retinoids may result in hypervitaminosis A and additive toxicities. Patients may be at increased risk for… | 5 sources — open the full entry |
| Selpercatinib | Moderate | Metabolism | Coadministration with selpercatinib may increase the plasma concentrations of drugs that are primarily metabolized by the CYP450 2C8 isoenzyme. The mechanism… | 2 sources — open the full entry |
| Sevelamer Carbonate | Moderate | Absorption | INTERVAL: Bile acid sequestrants and the phosphate binder, sevelamer, can decrease the absorption of fat-soluble vitamins A, D, E, and K. In non-clinical… | 7 sources — open the full entry |
| Sevelamer Hydrochloride | Moderate | Absorption | INTERVAL: Bile acid sequestrants and the phosphate binder, sevelamer, can decrease the absorption of fat-soluble vitamins A, D, E, and K. In non-clinical… | 7 sources — open the full entry |
| Orlistat | Minor | Absorption | Orlistat decreases the absorption of fat-soluble vitamins. Vitamin supplements should be taken at least two hours before or after orlistat administration. | 1 sources — open the full entry |
Conditions
Conditions in which Vitamin A needs care, as documented in this source.
Liver Diseases
MajorVitamin A (including beta-carotene) is fat soluble and requires bile for adequate intestinal absorption. Hepatic and/or biliary dysfunction decrease the absorption of vitamin A. Vitamin A is metabolized by the liver and primarily excreted in bile and feces. Beta-carotene is primarily metabolized in the GI mucosa to vitamin A. Hepatic and/or biliary impairment can alter the metabolic and therapeutic activity of Vitamin A.
1 source
- "Product Information. Aquasol A (vitamin A)." Hospira Inc (2022):
Malabsorption Syndromes
ModerateAbsorption of vitamin A depends on the presence of bile and absorbable fat in the GI tract. Prolonged fat malabsorption (cystic fibrosis, hepatic cirrhosis, sprue) or malabsorption syndromes (celiac disease, GI resection) can decrease the absorption of Vitamin A. Water- miscible vitamin A formulations may be an appropriate alternative in malabsorption conditions for certain conditions requiring vitamin A therapy.
1 source
- "Product Information. Aquasol A (vitamin A)." Hospira Inc (2022):