Vitamin C + Vitamin E interactions
Checked as Vitamin E in this data source.
Full monograph for Vitamin C + Vitamin ECheck it against another medicine
Medicines
161 documented
Mechanism
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Ibrutinib | Major | Synergy | Coadministration of ibrutinib and drugs that interfere with platelet function or coagulation may potentiate the risk of bleeding complications. | 6 sources — open the full entry |
| Allium cepa + Heparin + Allantoin | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Apixaban | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Arsenic Trioxide | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Aspirin | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Aspirin + Dipyridamole | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and…2 documented mechanisms | 20 sources — open the full entry |
| Azacitidine | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Bendamustine | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Betrixaban | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Bivalirudin | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Bleomycin Sulfate | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Bortezomib | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Cabazitaxel | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Capecitabine | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Carbonyl Iron + Folic Acid | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Carbonyl Iron + Folic Acid + Zinc Sulfate | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Carbonyl Iron + Folic Acid + Zinc Sulfate + Vitamin B Complex + Vitamin C | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Carboplatin | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Carfilzomib | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Carmustine | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Chlorambucil | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Cilostazol | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Cisplatin | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Clopidogrel + Aspirin | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and…2 documented mechanisms | 20 sources — open the full entry |
| Clopidogrel Bisulphate | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Cyclophosphamide | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Cytarabine | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Dabigatran Etexilate Mesylate | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Dacarbazine | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Dalteparin Sodium | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Daunorubicin | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Decitabine | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Dipyridamole | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Docetaxel Trihydrate | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Doxorubicin Hydrochloride | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Doxorubicin Hydrochloride Liposome | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Enoxaparin Sodium | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Epirubicin Hydrochloride | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Eptifibatide | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
| Eribulin Mesylate | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Etoposide | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Ferric Carboxymaltose | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Ferric Derisomaltose | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Ferric Maltol | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Ferric Pyrophosphate Citrate | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Ferrous Fumarate + Folic acid | Moderate | Antagonism | Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. | 2 sources — open the full entry |
| Fludarabine Phosphate | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Fluorouracil | Moderate | Others | The potential effects of vitamin E on cancer chemotherapy and radiation have not been established. Because vitamin E is an antioxidant, pharmacologic doses… | 9 sources — open the full entry |
| Fondaparinux Sodium | Moderate | Synergy | Vitamin E may potentiate the effects of anticoagulants and platelet inhibitors. Vitamin E is thought to inhibit the oxidation of reduced vitamin K and… | 20 sources — open the full entry |
Conditions
Conditions in which Vitamin C + Vitamin E needs care, as documented in this source.
Liver Diseases
MajorVitamin E is fat soluble and many oral formulations require bile for adequate intestinal absorption. Hepatic and/or biliary dysfunction decrease the absorption of vitamin E. Water- miscible vitamin E formulations may be better absorbed from the GI tract under these conditions. Vitamin E is metabolized by the liver and primarily excreted in bile and feces. Hepatic and/or biliary impairment can alter the metabolic and therapeutic activity of vitamin E.
1 source
- "Product Information. Aquasol E (vitamin E)." Apothecon Inc (2022):
Malabsorption Syndromes
MinorVitamin E is readily absorbed from the intestinal tract in the presence of bile. Prolonged fat malabsorption (cystic fibrosis, hepatic cirrhosis, sprue) or malabsorption syndromes (celiac disease, GI resection) can decrease the absorption of many oral formulations of vitamin E. A water- miscible formulation of vitamin E may be better absorbed in these conditions.
1 source
- "Product Information. Aquasol E (vitamin E)." Apothecon Inc (2022):